Symptoms – Listorati https://listorati.com Fascinating facts and lists, bizarre, wonderful, and fun Mon, 24 Nov 2025 04:49:30 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 https://listorati.com/wp-content/uploads/2023/02/listorati-512x512-1.png Symptoms – Listorati https://listorati.com 32 32 215494684 10 Modern Symptoms – Quirks from Millennials to Listicles https://listorati.com/10-symptoms-modern-quirks-millennials-listicles/ https://listorati.com/10-symptoms-modern-quirks-millennials-listicles/#respond Sat, 22 Mar 2025 12:53:49 +0000 https://listorati.com/10-symptoms-of-the-modern-world-that-arent-modern-at-all/

From Victorian selfies and Ancient Rome’s own version of Facebook to a medieval brand of atheism that would make today’s skeptics blush, the world’s quirkiest habits aren’t as fresh as they feel. The phrase 10 symptoms modern captures the idea that what we label “new” often has deep‑rooted ancestors. In this roundup we’ll travel from lazy millennials to the timeless allure of listicles, proving that history loves to repeat its favorite jokes.

Why 10 Symptoms Modern Matter Today

10 Millennials

Millennials modern selfie culture - 10 symptoms modern illustration

They’re portrayed as lazy, entitled narcissists who wouldn’t recognize a hard day’s work even if it smacked them in the face. Obsessed with selfies, Instagram, and a parade of frivolous distractions, millennials are often painted as the epitome of modern indolence.

Even though the label “millennials” is a recent addition to our lexicon, the traits we now slap on them have been tossed around for centuries. It’s tempting to pin the downfall of Western culture on this generation, yet every era before us has faced similar accusations.

Back in 1968, Life ran a piece claiming that the phrase “to make a living” had lost all meaning for baby boomers, branding them as work‑shy wimps. Decades later, a New York Times writer turned the same glare on Generation X, calling them lazy and immature.

Reach further back to ancient Greece, and you’ll find Hesiod lamenting that the younger crowd “only cares about frivolous things.” While Hesiod never posted a selfie, the sentiment mirrors today’s complaints perfectly.

This doesn’t mean millennials lack their own quirks; it simply shows that each generation repeats the same set of criticisms that older folks have hurled at them for ages.

9 New Atheism

New Atheism historical roots - 10 symptoms modern visual

Atheism—the absence of belief in a deity—has existed forever. New Atheism, however, is the modern, in‑your‑face brand that shouts on Twitter, brands believers as gullible, and reframes atheism from simple non‑belief to active anti‑religion.

In the 10th‑century Abbasid world, Syrian thinker Abu al‑Ala’ al‑Maarri earned the nickname “the Richard Dawkins of his era.” He openly mocked religion, declaring the world split between “brains without religion” and “religion without brains,” and attracted a following that would have fit right into today’s satirical magazines.

Even earlier, the 9th‑century Baghdad philosopher Ibn al‑Rawandi denounced Islamic tradition as illogical, called miracles hoaxes, and labeled religion irrational. Like modern New Atheists, he provoked believers with blunt challenges—yet both he and al‑Maarri lived to old age without the violent backlash that often greets contemporary critics.

8 Selfies

Nothing screams “the end of culture!” quite like the modern selfie obsession, which many claim is the ultimate expression of narcissism. In reality, selfies have been around as long as cameras themselves.

During the Victorian and Edwardian eras, bulky cameras forced early selfie‑takers to rely on mirrors, but the core idea—capturing one’s own likeness—remains unchanged. In 1914, Russian princess Anastasia Nikolaevna Romanova produced what could be considered the first teenage selfie, striking a bored pose that looks eerily familiar on today’s Instagram feeds.

Even earlier, Belgian artist Henri Evenepoel was snapping self‑portraits as early as 1898, and World War I soldiers used Kodak cameras to send personal mementos home. Those wartime “selfies” are now treasured historical artifacts.

7 Insane Fan Fiction

Ancient fan fiction examples - 10 symptoms modern image

When you hear “fan fiction,” you probably picture misspelled tales of Kirk and Spock doing things that would make a seasoned adult blush. Yet fan‑created stories have been circulating long before the internet ever existed.

In the early Common Era, the Gnostic gospels acted as fan‑made rewrites of Christian narratives. For instance, the Egyptian Gnostic Basilides crafted a version where Simon of Cyrene is mistaken for Jesus and crucified, only for a laughing Jesus to stand beside the cross—an ancient echo of today’s alternate‑ending fanfic.

Fast forward to 1893: Arthur Conan Doyle killed off Sherlock Holmes, prompting a wave of Victorian fan writers to pen their own Holmes mysteries. The era’s fanfic frenzy was just as intense as today’s, merely lacking the modern GIFs of Benedict Cumberbatch.

6 Social Media

Depending on who you ask, social media is either a glorious global think‑tank or a chaotic arena where social‑justice warriors and alt‑right trolls clash. While it feels uniquely digital, historian Tom Standage argues that social media dates back to Roman times.

In his book Writing on the Wall: Social Media – The First 2,000 Years, Standage points to graffiti uncovered in Vesuvius taverns that reads like a back‑and‑forth conversation, complete with a classic trolling line: “Successus, a weaver, loves the innkeeper’s slave girl named Iris. She, however, does not love him. Bye, loser!” followed by a snarky reply.

He also highlights Roman abbreviations such as “SPD” (salutem plurimam dicit), which function much like today’s “LOL” or “NSFW.” Whether or not you call it true social media, the impulse to broadcast brief, witty messages is undeniably ancient.

5 Annoying Advertisements

Roman pop‑up ads - 10 symptoms modern representation

Romans were already perfecting the art of intrusive pop‑ups long before Don Draper ever existed.

Julius Caesar launched the Acta Diurna, an early newspaper that mixed propaganda with human‑interest stories—think heart‑warming animal tributes alongside plain‑spoken adverts. One surviving ad, posted by a fellow named Maius, shouted “second‑story apartments fit for a king!” on the daily wooden boards of the forum.

Wealthy Romans could even perform a primitive form of AdBlock by instructing a slave to copy the paper while skipping the commercial sections. And Rome wasn’t alone: in Thebes, 3,000‑year‑old written ads offering rewards for runaway slaves have been uncovered, proving that the annoyance of ads is truly timeless.

4 Overpaid, Hedonistic Sports Stars

Ancient sports stars wealth - 10 symptoms modern depiction

Modern athletes are often accused of being overpaid, booze‑loving tabloid fixtures. Yet the ancient world boasted sports icons whose wallets dwarfed today’s multimillion‑dollar contracts.

Take Gaius Appuleius Diocles, a 2nd‑century Roman chariot racer. Over a 24‑year career he started roughly 4,200 races, finishing first or second in about half of them. By the end, he amassed 36 million sesterces—enough to pay every Roman soldier’s salary for two months, equivalent to roughly $15 billion today, making him arguably the highest‑paid athlete in history.

Then there’s Milo of Croton, the legendary wrestler famed for his prodigious strength and prodigious drinking. Stories claim he could down eight quarts of wine in a single sitting. His demise was equally theatrical: an elderly Milo attempted to split a tree with his bare hands, became trapped, and—according to some accounts—was devoured by wolves.

3 Cash Grabs And Unimaginative Sequels

Early cinema cash‑grab sequels - 10 symptoms modern graphic

Calling today’s Hollywood “unoriginal” feels like a fresh accusation, yet the industry’s penchant for cash‑grab sequels dates back to cinema’s earliest days.

D.W. Griffith’s 1915 blockbuster Birth of a Nation shocked modern audiences with its glorified Klan portrayal. Its massive box‑office haul spurred an immediate sequel, Fall of a Nation (1916), which flopped spectacularly. Critics lambasted it as propaganda and “sometimes preposterous.” The sequel is now considered lost forever.

But the trend wasn’t confined to film. After H.G. Wells released War of the Worlds, author Garrett P. Serviss rushed out an unauthorized sequel where Thomas Edison flies to Mars to kick Martian butt. Even earlier, an illicit continuation of Cervantes’ Don Quixote outraged the original author, prompting him to finish his masterpiece.

2 Modern Disney Stories

Disney fairy‑tale ancestry - 10 symptoms modern visual

Most Disney hits feel fresh, yet many are rooted in centuries‑old folklore. Frozen adapts a Hans Christian Andersen tale; Tangled retells the classic Rapunzel story. Recent scholarship suggests that a surprising number of these narratives predate the 1500s by millennia.

A study in Royal Society Open Science traced the ancestry of tales across 50 Indo‑European languages, finding that roughly a quarter have deep, ancient lineages. “Jack and the Beanstalk,” for example, was linked to a 5,000‑year‑old tradition dating back to the split between Western and Eastern Indo‑European branches. Other stories, like Beauty and the Beast, may be a full millennium older than commonly believed.

The researchers even identified a tale dubbed “The Smith and the Devil” that likely originated in the Bronze Age. If Disney ever turned that into a feature, it would hold the record for the longest gap between oral tradition and cinematic adaptation.

1 Listicles

Historic listicle example - 10 symptoms modern illustration

Journalists love to gripe about listicles, yet the format has been a staple of human communication for centuries. Modern outlets publish tongue‑in‑cheek titles like “35 Reasons I Hate Lists,” but the disdain is hardly new.

One 19th‑century example, “The Fate of the Apostles,” was hailed by Smithsonian Magazine as a viral sensation of its day. It cataloged the deaths of Jesus’s apostles in chronological order and was reprinted roughly 110 times—equivalent today to a list being featured on The Guardian, CNN, BBC, and The New York Times simultaneously.

Even the greats were list‑makers: Leonardo da Vinci and Benjamin Franklin kept meticulous lists, while literary figures like Umberto Eco argue that Homer and Thomas Mann embedded list structures in their works. As Eco famously said, “The list doesn’t destroy culture; it creates it.”

So the next time you scroll past a numbered roundup, remember: you’re part of a tradition that stretches back to antiquity, proving that humans have always loved to rank, organize, and—yes—occasionally brag about it.

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10 Dying Symptoms: Rome’s Final Warning Signs Unveiled https://listorati.com/10-dying-symptoms-rome-final-warning-signs-unveiled/ https://listorati.com/10-dying-symptoms-rome-final-warning-signs-unveiled/#respond Mon, 28 Oct 2024 21:10:30 +0000 https://listorati.com/10-dying-symptoms-of-the-roman-empire/

The saga of the Roman Empire’s slow‑motion collapse is a perennial favorite for history buffs. The very fact that a civilization as mighty as Rome could crumble serves as a stark reminder to any power that finds itself perched atop the world stage. While many point to the accession of Commodus in AD 180 as the opening act, the real fatal flaws had been festering long before. In this countdown we’ll walk through the ten dying symptoms that together spelled the end for the mighty empire.

10 Unclear Succession System

Unclear succession system – Roman imperial instability

Augustus, the empire’s inaugural ruler, never managed to lock down a clean‑cut line of inheritance. The result? Whenever a throne needed a new occupant, a crowd of ambitious claimants surged forward, each hoping to outmaneuver the others.

Some aspirants even had a vested interest in hastening the incumbent’s demise so they could swoop in and claim the purple for themselves. This ruthless jockeying helped cement a long‑standing pattern of assassination plots that peppered the imperial timeline.

The succession machinery proved fragile and volatile. In the first two centuries of imperial rule, only Titus (r. AD 79‑81) succeeded his own father, Vespasian. It wasn’t until Commodus in AD 161 that a sitting emperor actually fathered his successor, Marcus Aurelius, marking a rare instance of hereditary transfer.

9 Currency Debasening

Currency debasening – Roman denarius losing silver

When Emperor Nero ran into a fiscal crunch, he opted for a classic short‑term fix: diluting the coinage. By trimming the precious metal content of the denarius, Nero hoped the public would still accept the coins at face value, even as their intrinsic worth slipped away.

This practice didn’t stay confined to Nero’s reign. Subsequent emperors followed suit, steadily eroding the silver purity of the empire’s backbone money. Under Nero the denarius boasted roughly 91.8 % silver; by the time Marcus Aurelius ruled, it had fallen to about 76.2 %; and by Septimius Severus’s era the metal content dwindled further to roughly 58.3 %.

The relentless debasening set the stage for a cascade of economic woes, as each successive emperor leaned harder on the same trick, eroding confidence in Rome’s currency with every tweak.

8 Inflation

Inflation in Rome – hoarded coins and soaring prices

With the coinage increasingly stripped of value, inflation surged through the empire. By AD 301, Emperor Diocletian felt compelled to issue his famous Edict on Prices, a desperate attempt to clamp down on spiralling costs. Yet even that sweeping decree barely dented the problem.

Price hikes were dramatic: wheat in Roman Egypt, which sold for six drachmas in the first century AD, ballooned to 200 drachmas by AD 276. By AD 324 the same staple fetched a staggering 78,000 drachmas, and by AD 334 it had exploded to over two million drachmas. Even basic pork, priced at 12 denarii under the edict, cost a jaw‑dropping 90 denarii by AD 412.

One side effect of this runaway inflation was a rush to hoard the few “good” coins that still retained precious metal. Archaeologists have uncovered countless hoards from the late empire, a silent testament to the public’s mistrust of the debased money.

7 The Year Of The Four Emperors

The year of four emperors – chaotic Roman succession

The period AD 68‑69 earned the dramatic moniker “The Year of the Four Emperors,” a grim prelude to the endless power struggles that would later plague the empire. After Nero’s death in June 68, three short‑lived rulers scrambled for the throne.

Galba ruled a mere seven months before meeting assassination; Otho lasted three months before taking his own life; and Vitellius survived eight months only to be slain. Finally, Vespasian emerged victorious in AD 69, ushering in a brief period of stability.

The chaos of that year is captured vividly by the historian Tacitus, who wrote, “The history on which I am entering is that of a period rich in disasters, terrible with battles, torn by civil struggles, horrible even in peace and four emperors killed by the sword.”

6 Army’s Diminishing Returns

Roman army’s diminishing returns – from conquest to defense

In the Republic and early Empire, the Roman legions thrived on the spoils of conquest. Each new province supplied fresh land, slaves, taxpayers, and treasure, effectively financing the military’s appetite for glory.

Once the empire reached its territorial zenith, the army’s role flipped to largely defensive duties. No longer could soldiers count on plunder to line their pockets; instead, the state had to fund them through taxation alone.

Ironically, this once‑glorious instrument of expansion became a financial drain. The ever‑growing tax burden to sustain the legions pushed many middle‑class Romans into poverty, eroding the very social fabric that had underpinned Rome’s ascent.

5 Barbarian Pressure

Barbarian pressure – invasions that shook Rome

For years, scholars pointed to barbarian invasions as the chief culprit behind Rome’s downfall. While the pressure from external tribes certainly mattered, it was only one piece of a larger puzzle.

Repeated waves of Germanic and other “barbarian” armies battered both the northern and eastern frontiers, gradually eroding the empire’s size. Britain fell in AD 406 when legions were recalled to defend the mainland against the Huns, and the Visigoths sacked Rome in AD 410 under Alaric’s command.

By AD 455, the Vandals seized Spain and North Africa, even pillaging Rome again that same year. What set this era apart was the stark incompetence of the Roman army, which could no longer repel invaders as it had so often done in earlier centuries.

4 Praetorian Guard Corruption

Praetorian guard corruption – power brokers of Rome

The Praetorian Guard began as an elite cohort tasked with protecting the emperor, but over time they grew into kingmakers, often backing candidates who promised them favors.

Their influence swelled to the point where they could literally install or eliminate emperors at will. In many instances, the Guard turned on the very ruler they were meant to protect, sealing his fate with a swift sword.

A particularly egregious practice was the “donative,” a hefty cash reward paid to the Guard by would‑be emperors. Pretenders would promise generous donatives to win the Guard’s loyalty, effectively buying the throne.

By the third century, no emperor could hope to govern without the explicit backing of the military, especially the Praetorian Guard. Their meddling turned succession into a chaotic, blood‑stained affair, with many rulers meeting their end at the hands of their own bodyguards eager for a payout.

3 Concentration Of Wealth

Wealth concentration – stark inequality in Rome

While the Roman Empire often conjures images of grandeur, it was also a society riddled with severe inequality. Agriculture formed the backbone of the economy, yet over 90 % of the late‑imperial population lived as rural paupers, scraping by on precarious livelihoods.

This disparity created a stark urban‑rural divide. Cities were often viewed as “predators” that extracted labor from the countryside, exhausting the land and deepening the plight of the peasantry. Osteological studies of Roman skeletons reveal widespread malnutrition, underscoring the grim health conditions of the majority.

The concentration of wealth in the hands of a privileged few not only strained social cohesion but also left the empire vulnerable to internal decay, as the majority of citizens bore the brunt of fiscal and food shortages.

2 Size Of The Empire

Size of the empire – sprawling Roman territories

The sheer expanse of Rome’s dominion bred a host of logistical nightmares. Journeys across the empire could take weeks, and the massive borders demanded an enormous standing army to guard them.

Ultimately, the empire became too vast to be effectively ruled from a single capital. Emperor Diocletian responded by splitting the realm into a Western half, centered on Rome, and an Eastern half, with Byzantium (later Constantinople) as its seat.

This division highlighted the limits of territorial overreach. Scholars still debate how the sheer scale of Rome contributed to its vulnerability, offering lessons on the challenges of governing sprawling polities.

1 Romulus Augustulus Deposition

Romulus Augustulus deposition – end of the Western Empire

On September 4, AD 476, the final Western Roman emperor, Romulus Augustulus, was overthrown by the Germanic chieftain Odoacer, a veteran of the Roman army who had risen to the rank of general.

While the removal of an emperor by a military leader was not unprecedented, this event was unique: no successor was appointed, and Odoacer crowned himself king of Italy, marking a definitive end to the Western imperial line.

By this point, the Western Empire was a shadow of its former self. The capital had already shifted from Rome to Ravenna, and the once‑vast western territories had fragmented into smaller kingdoms and city‑states. The Eastern Roman Empire, however, clung on, preserving imperial traditions until its ultimate fall in 1453.

Why These 10 Dying Symptoms Matter

The phrase “10 dying symptoms” perfectly captures the cascade of internal failures that accelerated Rome’s demise. From a shaky succession plan to runaway inflation, each symptom acted like a wound that never healed, collectively ensuring the empire’s eventual collapse.

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10 Dreadful Symptoms That Reveal Hidden Deadly Diseases https://listorati.com/10-dreadful-symptoms-reveal-hidden-deadly-diseases/ https://listorati.com/10-dreadful-symptoms-reveal-hidden-deadly-diseases/#respond Sat, 11 May 2024 06:17:02 +0000 https://listorati.com/10-dreadful-symptoms-of-deadly-diseases/

The human body is a marvel of engineering: it can juggle absurd demands, mend its own wounds, nourish itself, and, most importantly, act as a vigilant guardian against danger. Yet, our grasp of the body’s deepest mysteries remains incomplete. Frequently, we encounter unfamiliar illnesses that were once the stuff of folklore or simply bizarre to the uninitiated. Below, we unveil 10 truly odd warning signs that could betray a lethal disease lurking beneath the surface.

10 Forgetting To Breathe

Brain pressure causing breathing failure - 10 dreadful symptoms

Yes, you read that correctly—people can actually forget to breathe. When intracranial pressure mounts—whether from a massive hemorrhagic stroke, an expanding tumor, or a buildup of cerebrospinal fluid (hydrocephalus)—the brain gets squeezed against the skull. This compression can reach the brainstem, where the respiratory centers reside, effectively shutting down the automatic urge to inhale.

The age‑old morbid joke about “forgetting to breathe” isn’t just dark humor; it signals a dire rise in intracranial pressure that, if untreated, can culminate in death.

Why 10 Dreadful Symptoms Matter

Spotting these warning signs early can be the difference between life and death. Recognizing that a seemingly absurd symptom may herald a catastrophic condition is essential for prompt medical intervention.

9 ‘Dancing’

Hemiballismus causing uncontrollable dancing movements - 10 dreadful symptoms

Imagine an uncontrollable urge to move as if a relentless beat were commanding your limbs. In medical terms, this isn’t a love for club music but a pathological phenomenon known as hemiballismus, where the brain’s inhibitory pathways fail, producing wild, jerky motions that onlookers might liken to a frantic dance.

Although fascinating at first glance, hemiballismus is profoundly disabling and often requires aggressive pharmacologic control to curb the incessant, involuntary flailing.

8 Hypersexuality

Hemiballismus causing uncontrollable dancing movements - 10 dreadful symptoms

It’s a common joke that men hail from Mars and women from Venus, but the true driver of sexual desire lies deeper within the brain. Hypersexuality, along with inappropriate sexual conduct and an odd fascination with oral exploration, belongs to the symptom cluster of Kluver‑Bucy syndrome—a rare condition that follows extensive damage to the brain’s limbic structures that normally rein in such impulses.

Unfortunately, neither psychotherapy nor medication can fully reinstate normal inhibition, leaving patients perpetually irritable and, frankly, overly aroused by virtually anything.

7 Complete Paralysis While Completely Awake

Locked‑in syndrome illustration - 10 dreadful symptoms

The notion of being fully conscious yet utterly immobile reads like a horror‑film script. In reality, this terrifying state—known as locked‑in syndrome—occurs when massive, yet non‑lethal, brain injury leaves a patient aware but unable to move, speak, or feel, essentially trapped inside their own body.

Recovery odds are bleak; most individuals remain in this condition until they pass away. Notable cases include the famed physicist Stephen Hawking (who lived with ALS), Rom Houben—a crash survivor who endured 23 years of confinement, and French philanthropist Jean‑Dominique Bauby, whose memoir famously chronicled his experience.

6 Testicles Larger Than Your Body

Elephantiasis affecting genitals - 10 dreadful symptoms

Picture genitalia so swollen they dwarf the rest of your torso. This grotesque presentation stems from elephantiasis, a condition where filarial worms—tiny parasites prevalent in certain African soils—invade the lymphatic system, blocking drainage and causing massive fluid accumulation beneath the skin, including the scrotum.

While elephantiasis can also manifest as enlarged feet or legs, the scrotal swelling, sometimes termed hydrocoele (or hematocoele when blood fills the space), is particularly alarming. Fortunately, when diagnosed early, most cases are highly treatable, underscoring the importance of regular self‑examination for men.

5 ‘Burning Up’

Malignant hyperthermia during surgery - 10 dreadful symptoms

Ever felt so furious you could burst into flames? Medically, the closest parallel is malignant hyperthermia—a rare, life‑threatening reaction to certain anesthetic agents during surgery. The body’s core temperature can skyrocket to 41 °C (105 °F), wreaking havoc on tissues unaccustomed to such heat.

This syndrome often stems from an inherited defect in the muscle’s calcium regulation pathway. Most patients remain oblivious to their susceptibility until a post‑operative crisis forces them into intensive care, giving a whole new meaning to being “hot” in the operating room.

4 Being Hurt By Sunlight

Porphyria patient avoiding sunlight - 10 dreadful symptoms

No, we’re not talking about vampires. The condition that fuels those nocturnal legends is porphyria, a group of metabolic disorders where the body accumulates porphyrins because it cannot synthesize heme properly. Certain forms cause extreme photosensitivity, turning sunlight into a painful, burning assault on the skin.

Patients also develop a ghostly pallor, an aversion to garlic (which can exacerbate symptoms), and urine that darkens to a purplish hue. Though exceedingly rare today, porphyria still haunts medical textbooks as the classic “vampire disease.”

3 Fear Of Water

Rabies causing hydrophobia - 10 dreadful symptoms

We all know dogs and cats may dislike baths, but a genuine dread of water in humans is a tell‑tale sign of rabies. The virus triggers violent spasms in the throat muscles, making swallowing excruciatingly painful. This “hydrophobia” isn’t a true fear of water but a physiological response that mimics it.

Because rabies is almost invariably fatal once symptoms appear, any bite from a potentially infected animal warrants immediate medical attention and post‑exposure prophylaxis.

2 Completely Ignoring A Body Part

Neglect syndrome after stroke - 10 dreadful symptoms

Forgetting where your car keys are is one thing; denying the existence of an entire limb is another. Stroke survivors sometimes experience a phenomenon called neglect, where they act as though a side of their body—or even the whole side—doesn’t exist, despite being physically intact.

Beyond mere weakness, this syndrome arises from damage to cortical areas that normally integrate spatial awareness, causing the brain to “ignore” the affected side entirely.

1 Self‑Mutilation

Lesch‑Nyhan syndrome causing self‑harm - 10 dreadful symptoms

Self‑harm is often linked to psychological distress, yet in Lesch‑Nyhan syndrome (LNS), a genetic disorder that impairs the recycling of uric acid, patients compulsively bite, chew, or gouge their own lips, tongue, and fingers. The excess uric acid builds up in the brain, triggering severe neurological and behavioral disturbances.

LNS patients exhibit an unrelenting drive to self‑injure, a symptom that appears purely psychiatric but actually stems from the underlying metabolic defect.

Dr. Keith Andrew Chan, an internist with a penchant for video games, frequently writes about such oddities, sharing insights in various health publications and offering a quirky perspective on these unsettling conditions.

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10 Bizarre Symptoms That Will Make You Do a Double Take https://listorati.com/10-bizarre-symptoms-double-take/ https://listorati.com/10-bizarre-symptoms-double-take/#respond Thu, 29 Jun 2023 19:08:15 +0000 https://listorati.com/10-bizarre-symptoms-of-common-conditions/

When it comes to feeling under the weather, most of us picture a runny nose or a sore throat. Yet the world of medicine hides a trove of 10 bizarre symptoms that can catch anyone off guard, even when the underlying condition is one we think we know inside‑out. Below, we dive into ten truly odd manifestations, each more surprising than the last.

10 People With Diabetes Insipidus Need to Drink Up to 20 Liters a Day

Bottled water representing excessive fluid intake - 10 bizarre symptoms context

When the pancreas fails to manufacture enough insulin—or any insulin at all—the condition we label diabetes mellitus takes hold. This classic form of diabetes has been tamed over the decades thanks to the pioneering work of Frederick Banting, who first coaxed insulin from animal pancreases, allowing countless sufferers to live long, productive lives. Still, the disease carries a suite of well‑known complications such as ketoacidosis, diabetic coma, and peripheral neuropathy.

What many people overlook, however, is the astonishing fluid‑intake requirement faced by a far less common cousin: diabetes insipidus. Unlike its sugary sibling, this disorder does not involve insulin at all. Instead, the kidneys lose the ability to concentrate urine, forcing the body to expel massive volumes of dilute fluid.

Individuals with diabetes insipidus can produce as much as twenty liters of urine each day—an amount that dwarfs the average person’s one to three liters. To stave off dangerous dehydration, they must replace that loss by drinking an equally staggering amount of water, often up to twenty liters daily. Without this relentless hydration, the condition can quickly become life‑threatening.

9 Extreme Cases of Anorexia May Result in a Layer of Fine Body Hair

Scale illustrating weight loss and lanugo hair - 10 bizarre symptoms

The mental‑health diagnosis of anorexia nervosa carries the grim distinction of being the deadliest psychiatric disorder. While the primary battle revolves around severe calorie restriction, the physical toll can be equally brutal. One of the most striking, yet little‑discussed, side effects is the emergence of lanugo—a soft, downy coat of fine hair that covers the body.

Lanugo is a normal feature of fetal development, serving as insulation for newborns still adjusting to life outside the womb. In most infants, this fuzzy layer disappears shortly after birth. However, when a person endures extreme malnutrition, the body may reactivate this ancient protective mechanism.

The resurgence of lanugo in individuals with eating disorders functions much like it does for newborns: it provides a thin barrier of insulation to help preserve body heat when the body’s energy reserves are dangerously low. The presence of this fine hair, often described as a “soft, downy coating,” is a clear signal that the body is in a state of crisis.

8 Too Much Vitamin A Can Cause Your Skin to Come Off

Vitamin D supplement bottle showing vitamin A toxicity - 10 bizarre symptoms

Imagine reaching for a hearty serving of polar‑bear liver, only to discover that the vitamin A content is enough to wreak havoc on your body. Hypervitaminosis A, the toxic overload of vitamin A, can occur when one ingests excessively high amounts of this fat‑soluble vitamin—something that can happen with the consumption of certain Arctic animal livers.

Typical side effects of vitamin A overdose include headaches, vomiting, blurred vision, and liver damage. Yet the most grotesque manifestation is the shedding of skin in large, painful sheets. Victims report that multiple layers of epidermis peel away, leaving raw, red tissue exposed. In one notorious account, an explorer stripped the soles of his feet, his ears, and even his genitals, as if the skin were sloughing off like a snake’s.

To put the danger in perspective, a single ounce of polar‑bear liver contains roughly nine million International Units (IU) of vitamin A—far exceeding the toxic threshold of 250,000 to 300,000 IU. Other Arctic creatures such as walrus, seal, reindeer, and arctic fox also pack dangerously high concentrations, making them potential sources of accidental overdose.

7 Severe Hypothermia Can Cause You to Strip Naked and Hide

Antarctic landscape depicting hypothermia extremes - 10 bizarre symptoms

When the body’s core temperature plummets, the classic signs—shivering, confusion, loss of coordination—are only the tip of the iceberg. In the most extreme stages of hypothermia, a bewildering set of behaviors can emerge, collectively known as “terminal burrowing” and “paradoxical undressing.”

Terminal burrowing drives victims to seek out the smallest, most enclosed space they can find—often crawling under a bed, behind furniture, or even attempting to dig a shallow pit, as if preparing for hibernation. This instinctual move is the body’s desperate attempt to shield itself from the cold, even if the chosen shelter offers little real protection.

Paradoxical undressing, on the other hand, sees individuals ripping off every article of clothing despite the frigid environment. The phenomenon stems from a sudden peripheral vasodilation: after prolonged constriction of blood vessels to preserve core heat, the vessels relax, flooding the extremities with warm blood. The sudden rush creates an intense sensation of heat, prompting the person to discard clothing in an effort to cool down—an action that, tragically, only accelerates heat loss.

6 A Sense of Impending Doom Is a Side Effect of Wrong Blood Type Transfusions

Blood bag illustration for ABO incompatibility - 10 bizarre symptoms

ABO incompatibility arises when a patient receives a blood transfusion that does not match their own blood type. While modern medicine has made such mismatches exceedingly rare, the consequences can be dramatic. Typical symptoms include fever, back pain, and hematuria, but one of the most unsettling manifestations is a profound sense of impending doom.

This eerie feeling—a vague, overwhelming conviction that something catastrophic is about to happen—does not stem from any physical ailment. Instead, it is a neuro‑psychological response, similar to the sensation reported after certain medication reactions or even after a jellyfish sting. The patient cannot pinpoint a cause; the dread is simply there, pervasive and unsettling.

5 Nicotine Withdrawal Can Cause a Sense of Time Dilation

Cigarette pack representing nicotine withdrawal - 10 bizarre symptoms

Quitting smoking cold turkey is notoriously tough, not just because of cravings but also due to the way nicotine reshapes perception. While irritability and anxiety are well‑known withdrawal symptoms, a less obvious effect is the distortion of time itself.

Research shows that people in nicotine withdrawal can overestimate the length of short intervals by as much as fifty percent. A 45‑second pause may feel like a minute and a half, making each moment seem interminably long. This temporal stretching amplifies feelings of frustration, feeding a vicious cycle of discomfort.

In controlled experiments, participants were asked to gauge a 45‑second interval. Those who had abstained from cigarettes guessed significantly longer than both non‑smokers and smokers who were allowed to light up during the test. The result: a clear, measurable “time warp” that accompanies nicotine withdrawal.

4 Covid‑19 Is Proving To Have Several Odd Symptoms

COVID-19 virus graphic showing unusual symptoms - 10 bizarre symptoms

The coronavirus pandemic continues to surprise clinicians with a roster of unexpected manifestations. Beyond the familiar cough, fever, and loss of smell, some patients report truly bizarre symptoms that challenge our understanding of the virus.

One such oddity is acquired prosopagnosia, commonly known as face blindness. Affected individuals suddenly lose the ability to recognize familiar faces, even those of close friends or family members, while still being able to identify voices and other cues. In pediatric cases, an unusual presentation includes conjunctivitis—commonly called pink eye—appearing as a primary symptom, a condition traditionally linked to bacterial infections.

3 Parkinson’s Can Cause Tiny Handwriting

Pencil writing tiny letters for Parkinson micrographia - 10 bizarre symptoms

Parkinson’s disease is widely recognized for its motor symptoms: tremors, rigidity, and slowed movement. Yet the condition also produces subtle, non‑motor signs that can serve as early warning lights for clinicians.

One such sign is micrographia, a dramatic reduction in the size of a person’s handwriting. As the disease progresses, the letters become increasingly cramped and diminutive, often making the writing virtually illegible. This tiny script reflects the same brain regions that govern movement, offering a clue that Parkinson’s may be lurking before more obvious symptoms appear.

2 Pregnancy Can Cause Pitting Edema

Pregnant belly showing swelling and pitting edema - 10 bizarre symptoms

Swelling, or edema, is a common companion of pregnancy, especially during the third trimester. While most expect a gentle puffiness, a rare and striking form known as pitting edema can develop, allowing a fingertip to leave a noticeable dent in the swollen tissue.

This pronounced fluid buildup not only creates visible pits but has also been linked to weight gain associated with depression, adding a psychological dimension to the physical symptom. The combination of hormonal shifts and vascular changes makes this edema an especially noteworthy, if uncommon, pregnancy‑related oddity.

1 An American Cancer Patient Developed an Irish Accent

Irish landscape symbolizing unexpected accent syndrome - 10 bizarre symptoms

Foreign accent syndrome (FAS) typically follows a traumatic brain injury or stroke, causing a person to speak with an unexpected regional accent. Yet a startling case emerged when a North Carolina man, battling prostate cancer, began speaking with a pronounced Irish lilt two years after his diagnosis.

Doctors confirmed that the patient had never spent time in Ireland, had no prior exposure to the accent, and no psychiatric history that could explain the shift. The phenomenon was traced to a paraneoplastic neurological disorder, wherein the immune system’s fight against cancer mistakenly attacks parts of the brain involved in speech production.

This rare manifestation underscores how malignancies can provoke neurological quirks far beyond the usual fatigue or weight loss, reminding clinicians to keep an eye out for the truly bizarre.

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10 Symptoms of Being Sick (and the Good They Do) https://listorati.com/10-symptoms-of-being-sick-and-the-good-they-do/ https://listorati.com/10-symptoms-of-being-sick-and-the-good-they-do/#respond Fri, 10 Feb 2023 03:50:59 +0000 https://listorati.com/10-symptoms-of-being-sick-and-the-good-they-do/

No one likes to be sick, and in the age of Covid this hits home more than ever. The moment you get a cough or fever, you have to wonder if it’s just a cold or something worse. And even if it’s not a devastating and lethal illness, if you’re sick with anything, you’re going to be dealing with symptoms that make your life miserable, even if only for a few days. So when that happens, try to take some comfort in knowing that, as awful as you feel, each one of those symptoms is doing a job and trying to help you in some way.

10. Vomiting

Emetophobia is the technical term for a fear of vomiting and a surprising number of people suffer from it. Though, in a severe form, it’s rare. In general, as much as 8.8% of the population has at least a mild fear of throwing up. It’s not hard to understand, either, since vomiting is not all that enjoyable. So why does it have to happen at all?

Well, from a very basic standpoint, it seems clear that you vomit because your insides want something outside and they can’t wait. And that’s exactly what’s happening. Something has triggered your digestive system to suggest you ingested something bad. A toxin, a poison, something that is a severe irritant and your body no longer wants it around.

There are mechanical reasons for vomiting as well, such as conditions that affect the nerves and muscles in your stomach, or even stress, but that’s a different issue. As a symptom of an underlying virus or infection, vomiting is your body’s way of trying to speed your recovery by forcing the thing making you sick right back out.

9. Shivering

With many illnesses, you’ll find yourself running between temperature extremes. One minute you’re cold and the next hot. And while a fever has its own purpose, which we’ll mention shortly, what’s the point of feeling cold and shivering? 

Shivering when you’re sick and feeling cold is essentially stage one of a two stage process. The second part often leads to a fever, but they need to go hand in hand. Your body wants to heat up to fight off infection, but it can’t do that out of nowhere. You need to make the heat somehow and that’s what shivering is for.

Your muscles begin contracting and relaxing rapidly. That physical process creates heat. Once your body has reached a high enough temperature, the shivering stops and then a fever sets in. 

8. Fever

The process by which a fever works in your body is not something most people consider. You get sick, sometimes you get a fever. On a deeper level, many of us understand that this increase in temperature is your body’s way of trying to fight off an illness. But how?

Fevers can be triggered by a number of illnesses, be they infections or viruses, and more. Your body is reacting to something it understands as undesirable by producing white blood cells in a greater abundance. These white blood cells stimulate your hypothalamus, which is what generally keeps your body in balance. One of the things it maintains is temperature. In simple terms, it turns up your internal thermostat so you get hotter than normal. 

As blood vessels contract, your blood goes away from the outside of your body to the inside. You shiver, producing more heat, and your body warms up. 

Most viruses and bacteria function in a host body at a stable temperature. They can only handle so much variation. Your immune system forces your temperature to rise in an effort to kill off as much of the invading pathogen as possible and return you to good health. The problem, of course, is that a fever that goes too high can be a danger all on its own. 

7. Runny Nose

When you’re sick, everything in your body seeks to get the cause of the sickness out and, more often than not, it can only do that in a gross way. In the case of a runny nose, your body needs to amp up mucus production in the hope that whatever infectious thing is inside of you gets stuck and oozes out. 

With something like a cold, the pathogen making you sick managed to get past the mucus lining in your body, which is a natural filter. Your body responds by making something called cytokines, which are proteins that can move between cells and send signals throughout your body. In this case, they signal your immune system to increase mucus production. 

Excess mucus is used to clean the mucus lining and flush out any contaminants or pathogens that may have infected it. It’s like your body trying to powerwash itself from the inside, basically. Without this excess mucus production, you would be more inclined to either stay sick or get sicker.

6. Coughing and Sneezing

The dreaded cough is one of the first and most notable signs of a myriad of conditions that plague us, especially during the winter. Cold and flu season are the cough’s natural habitat. Like vomiting, coughing is a reflex action your body takes when it senses something that it doesn’t want inside of it. Unlike vomiting, it’s a little less picky about how it operates.

Basically, anything that irritates your breathing is going to cause coughing. That’s why a cold makes you cough, but so does smoking or getting a nose full of pepper by accident. Your body has sensed something that doesn’t belong in it and is trying to force it out with a blast of air that can actually propel things outwards at up to 50 miles per hour.  Sneezing performs essentially the same function.

As we just saw, mucus production is a by-product of many illnesses, so, in those cases, coughing is a complementary action that helps clear your airways to ensure you can keep breathing. On the other hand, various proteins in our immune response can cause inflammation in our throats and airways as a method of combating infection or viruses. A by-product of this is also a cough, since your airway is inflamed. The cough itself may not be eliminating anything in those cases. In general, however, both a cough and sneeze are working to remove pathogens from your airways.

5. Sore Throat

So what tends to come along with a cough, a fever, and excess mucus? A sore throat. Something like a chronic cough can exacerbate a sore throat and make it feel worse, but it’s not typically the root cause of a sore throat. That’s actually something we just mentioned when dealing with coughs – inflammation. 

You can think of inflammation as similar to a localized fever. The places in your body that become inflamed when you’re sick get red, they swell, and they warm up. Your body is trying to fight off something in that specific location where inflammation has occurred. Many of us think inflammation is caused by what’s wrong with us, but technically, is your body trying to fix what’s wrong with you. 

The inflammation triggers the production of white blood cells that go to the inflammation site to combat whatever infection is plaguing you. When the white blood cells and antibodies reach the site of the swelling, they put pressure on nerve endings. These two things together create the feeling of your throat being thick and swollen, as well as in pain. Uncomfortable though it may be, it’s a sign your body is working as it should to fight off the illness. 

4. Loss of Appetite

Getting sick often means losing your desire to do almost anything. And while you may not be in the mood to physically run around and do things, even necessary biological imperatives like eating can take a back seat. Loss of appetite is a very common symptom of many conditions. 

Blame the cytokines again for this one, as the suppression of appetite is a method your body uses to focus on healing. Digesting food can take up as much as 15% of the energy your body expends in a day. When you don’t eat, that energy can be used instead to help fight off the illness that you’re battling. 

The other potential reason is that, if you’re vomiting because you’re sick with an infection that’s giving you stomach issues, it’s pretty clear you don’t want or need to be putting more food inside of yourself at that moment. So your body is holding off on the desire to eat until you’re physically able to do so. 

3. Pus

Pus is probably one of the most unpleasant substances made in the human body. It’s thick and can sometimes smell just awful. It’s also a prime indicator of a seriously bad infection. But it’s not the infection itself, it’s your body’s response to an infection. As off putting as it may be, if you didn’t have the ability to produce pus then you’d probably be in a pretty bad way.

When you have an infection, pus builds up around it. It’s just white blood cells looking to eliminate that infection. Problems arise when the infection is worse than your immune system can handle. For instance, a foreign body can’t really be destroyed by white blood cells, so an infection will grow. Likewise, an abscess may only get larger as tissue dies and the infection grows bigger than your immune system can manage. 

Consider, however, that if you couldn’t produce pus, then your first line of defense against infection wouldn’t exist and even a small skin infection could potentially become deadly.

2. Drowsiness

For many of us, getting sick means spending the day in bed. Even when you go to the hospital, they put you in a bed. It’s probably the most prescribed treatment in the world for nearly every conceivable condition. So the fact that getting sick often makes you drowsy makes a lot of sense. 

Sleep is necessary for life, even if we don’t fully understand the mechanisms of everything that happens when you’re out for the night. But we do know it allows your body to take the time to repair itself from damage. When sick, sleeping is especially beneficial since you’re not wasting time on waking endeavors. Everything from digesting to thinking to moving takes energy your body could be using to heal when you’re awake. You’re just more efficient at healing when you’re asleep. 

Research has shown that in worms, certain nerve cells release neuropeptides when they’re ill. These neuropeptides stamp down the nervous system and make the worms fall asleep so they can heal. It’s been speculated a similar process is occurring in humans as well. 

1. Sickness Behavior

Sickness behavior may sound like a vague term, but it kind of has to be. It’s a blanket term for that hard to describe feeling when you know you’re sick. It’s everything we already described, and then how you deal with it when you experience it. You feel slow and gross and tired and weary. It doesn’t matter which sickness you have, sickness behavior is how you personally deal with it.

Cytokines and other proteins are at the root of your sickness behavior, the suite of awful symptoms you feel when you’re ill. And while some of the individual things have functions, which we’ve covered, the overall feeling of awfulness seems to exist as a measure of preservation and isolation. You feel awful to keep yourself from getting up and doing anything else. A sort of self-quarantine, really. Stop the spread of illness to others, stop the strain on yourself, and just focus on recovery.

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10 Genetic Conditions With Remarkably Weird Symptoms https://listorati.com/10-genetic-conditions-with-remarkably-weird-symptoms/ https://listorati.com/10-genetic-conditions-with-remarkably-weird-symptoms/#respond Wed, 08 Feb 2023 09:26:48 +0000 https://listorati.com/10-genetic-conditions-with-remarkably-weird-symptoms/

Usually when you hear about a genetic condition in the media, it’s presented as rare. You may be surprised to learn that around 60% of people will endure some kind of health problems related to a genetic condition. The symptoms can range from extremely mild to absolutely devastating. Many of the more common or severe conditions get a lot of media coverage, but there are numerous others which bring a host of unusual symptoms along with them that are lesser known. 

10. Angelman Syndrome

Angelman Syndrome affects about 1 in 12,000 to 20,000 people. Its cause is related to a problem with a gene on chromosome 15. Either the maternal copy of the gene is damaged in some way, or there are two paternal copies present.

Those with Angelman may have developmental delays and issues with balance and speech. However, there are some other characteristics of the condition which make it very unique. One of them is how it affects the disposition of children who are born with it. Though they may experience intellectual disabilities, children with Angelman’s are frequently noted to have remarkably happy and excited dispositions. Smiling and laughter are hallmarks of the syndrome. 

People with Angelman typically have a lifespan as long as those who don’t have the condition, although they may require lifelong assistance. Another unique aspect of the condition is that many of those diagnosed with it have a fascination with water

9. Snatiation

Snatiation may be a fun word to say, but it’s an odd condition to have. The name is a portmanteau combining “sneezing” with “satiation” and gives insight to what exactly happens when you suffer from the condition. Those who have it sneeze after they feel full from eating. 

First identified in 1989, the condition has been studied little because, let’s be honest, it’s not a pressing concern for most people. Basically, what happens is that, after eating a meal that fills you up, you’ll sneeze a handful of times. The case was first reported in a man who sneezed about four times after every meal, and most of his family did the same. So clearly it was genetic in nature. One person recorded 22 sneezes as a personal record. Annoying, to be sure, but not dangerous. 

The type of food has no effect on the condition, and the sneezing isn’t a continual, painful, or even disruptive thing, but it may happen for someone’s entire life. 

8. Favism

Favism sounds similar enough to favoritism that you may not even realize it’s related to a genetic condition at first. That said, it is a condition that affects people who are deficient in an enzyme called glucose-6-phosphate dehydrogenase. This enzyme is important to maintaining red blood cells. Now, even if you have the condition, you’ll likely be fine in general. The problem arises when a person who has it consumes certain compounds that can be found in medication or specific foods. When those are ingested, red blood cells can burst inside the body and lead to severe anemia.

So far it sounds like a curious condition, but not all that weird. That part comes in when you look at what triggers this anemia reaction. It’s fava beans, hence the name favism. You can also suffer the same fate by eating broad beans which are in the same family as fava beans and contain the same glucoside compounds.

The symptoms will manifest within six to 24 hours. Victims will become jaundiced and may have dark urine. The condition can potentially be life threatening. 

7. Klippel–Trénaunay Syndrome

Klippel–Trénaunay Syndrome can express itself in many ways. The congenital vascular disorder is very often denoted by dark-colored birthmarks as well as overactive bone or soft tissue growth.  For many people, it can be debilitating. Since it often presents in a single limb, it can lead to things like fingers or toes fusing. But for Matthias Schlitte, the German Hellboy, it turned out to be an odd blessing. 

Schlitte has confirmed he was born with the condition despite online rumors that he did this to himself. And in this case, the “this” we’re referring to is that arm. Schlitte is a professional arm wrestler because his Klippel–Trénaunay Syndrome caused his arm to grow unusually muscular. Though he looks like he spent his whole life only lifting weights with one arm, the condition is mostly responsible for what has happened 

He discovered when he was still a little boy that one arm was just much stronger than the other. Encouraged by his mother, he took up arm wrestling and has exploited it to his advantage. His arm grew to 46 centimeters, or about 18 inches in diameter, while the average bicep is under 14 inches

6. Adermatoglyphia 

By the numbers, the odds of a stranger somewhere in the world having the exact same fingerprints as you are one in 64 billion. As far as we know, it has never happened. But there is a much greater chance that someone in the world has no fingerprints at all, thanks to a condition called adermatoglyphia

One of the rarest conditions in the world and so far only linked to a few families, the only side effect seems to be entirely smooth finger pads. It first came to the attention of a dermatologist in 2007 when a patient came in with a problem. She couldn’t travel from Switzerland to the United States because she had no fingerprints, and no one had ever encountered that before. As it happened, many of her family members had the same problem.

A little digging turned up a mutation in a gene called SMARCAD1. How it caused them to not develop fingerprints is still unclear, and no other symptoms seem to come along with it. 

5. Short Sleep

The amount of sleep a person needs can vary based on several factors. The Mayo Clinic has a chart arranged by age with recommendations that range from seven hours for adults to as much as 16 hours for infants. But that seven plus hours is the absolute low end of the scale and doctors generally agree that lack of sleep can bring a host of serious health problems.

That said, there are some people in the world who are genetically short sleepers. A mutation of the DEC2 gene is the culprit. Those with the mutation can cut their sleep cycle much shorter, clocking a brisk four or five hours before waking up as refreshed as the rest of us who need a full seven or eight hours. 

In mice that had the same gene manipulated, the production of a hormone called orexin was altered. Orexin regulates wakefulness. Your body produces it when it’s time to wake up and a narcoleptic produces too little. But those with the altered gene make it earlier in a sleep cycle than the rest of us, to no ill effects. 

4. Total Color Blindness 

You can quickly find an online test for colorblindness and it’s likely to be a circle made of colored bubbles. There will be a number in the center formed of reddish bubbles surrounded by green bubbles. If you can’t read that number, you’re colorblind. But that’s just one kind of colorblindness, often called red-green colorblindness.

There are several ways a person can be colorblind, and red-green is the most common. Blue-yellow is another less common version and even more rare is monochromacy. This version affects one in 33,000 people and they see no color at all. The world is simply black and white. 

On the tiny island of Pingelap in the Pacific Oceans, monochromacy is very common. This is because, in 1780, a tsunami killed all but around 20 people on the island. The king, one of the survivors, had a genetic condition that caused monochromacy. He set about repopulating the island as best he could and his descendants carried the colorblindness gene,

Today, sufferers need to wear dark glasses during the day because the sun essentially blinds them. However, their night vision is remarkable. Around 10% of the island have the condition and, at night, they can work and function as well as most of the rest of us do in full daylight. 

3. Methemoglobinemia 

Skin tone can vary greatly from one person to another and for a variety of reasons. Typically, we’re all familiar with the common range of skin tones, however, and it’s rare that you would ever see a person whose skin tone could be described as surprising. This was not the case with the Fugate family, whose skin was blue. 

In the 1820s, in a place called Troublesome Creek, Kentucky, there was an entire family of blue-skinned humans. Martin Fugate, the patriarch, had skin described as being “indigo blue.” He married a woman named Elizabeth Smith, and four of their seven children also had blue skin. 

In the 1970s, a baby named Benjamin Stacy was born with skin the doctor described as “blue as Lake Louise.” He was the great grandson of Luna Fugate, herself the great granddaughter of Martin, and just as blue. 

Martin passed a condition called methemoglobinemia to his children and, as a result of inbreeding, the condition continued. The recessive gene remained in the family line and manifested again with Benjamin Stacy when he was born. Their hemoglobin can’t carry oxygen through the blood and many patients who have the condition, which can also be caused by medication, will die. But if enzyme levels are in the right balance, a person could live a full life as all of the Fugates did. They’ll just be bright blue. 

2. Honeymoon Rhinitis

Also called Honeymoon Nose, Honeymoon Rhinitis is a condition where sexual activity leads to nasal congestion and sneezing. The symptoms can manifest at any point during a sexual interaction but seem to occur most often right after. They are not caused by any direct stimulation of the nasal cavity or mucous membranes in the area. The cause is unknown.

It has been theorized that the condition may be caused by emotional stimulation and anxiety. It becomes a parasympathetic response as various hormones and emotions build during the activity and then, boom, your nose turns against you. Another theory has a psychiatric component, with sneezing being a physical manifestation of the emission of sexual tension. 

Both men and women can suffer from it, and it resolves itself once the situation is no longer present. That means when the sexy times are done, the symptoms leave in about five to 15 minutes.

One thing worth noting is that the condition isn’t necessarily predicated on actual sexual activity with a partner. It may even occur as a result of sexual thoughts, which could potentially be remarkably frustrating and embarrassing depending on circumstances. 

1. Fatal Familial Insomnia

If you’ve ever suffered insomnia or another sleep disorder, you know it can get bad fast. The feeling of exhaustion that refuses to go away and, in time, problems focusing and mood changes. Fatal familial insomnia is a genetic condition that takes this to terrifying new levels.

The condition is caused by a mutation in a gene that produces a cellular prion protein. It can manifest in a person’s 20s all the way to their 70s, though most victims are in their 40s when symptoms begin.Once they begin, a person may have between seven months and six years to live. It cannot be cured.

Symptoms start out as difficulty falling or staying asleep, what you’d consider typical of insomnia. As it progresses, there may be muscle spasms, stiffness, mental deterioration, rapid heart rate and finally death. 

Treatments involve measures to try to induce or maintain sleep, but they are only band aid solutions. Over time they fail to provide relief.

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